Figure 5.
Nuclear DOX delivery efficiencies of LB@TATp-MSN, TLS11a-LB@MSN, and TLS11a-LB@TATp-MSN in H22 cells. PBS/DOX, LB@TATp-MSN/DOX, TLS11a-LB@MSN/DOX, TLS11a-LB@TATp-MSN/DOX, and DOX were incubated with H22 cells for 2 h. (A) The cells were visualized under a fluorescent microscope for DOX in H22 cells. (B) The intensities of the intra-cellular fluorescence signals were determined using flow cytometry. (C) The mean intensities of the intra-cellular fluorescence were calculated. *P < 0.05, ***P < 0.001.