Table 3.
Clinicopathological Associations of PPP2R2A Expression in Primary PDAC
| Clinicopathological Parameters | No. of Patients | PPP2R2A | χ2 | P-value | |
|---|---|---|---|---|---|
| High | Low | ||||
| Cases | 60 | 12 | 48 | ||
| Age (years) | |||||
| ≤60 | 35 | 8 | 27 | 0.429 | 0.513 |
| >60 | 25 | 4 | 21 | ||
| Gender | |||||
| Male | 34 | 8 | 26 | 0.611 | 0.434 |
| Female | 26 | 4 | 22 | ||
| Tumor location | |||||
| Head | 43 | 7 | 36 | 1.313 | 0.252 |
| Body-tail | 17 | 5 | 12 | ||
| Tumor size (cm) | |||||
| <2.5 | 18 | 7 | 11 | 5.734 | 0.017* |
| ≥2.5 | 42 | 5 | 37 | ||
| Differentiation | |||||
| Well | 19 | 3 | 16 | 0.308 | 0.579 |
| Moderate and poor | 41 | 9 | 32 | ||
| T stage | |||||
| T1+T2 | 55 | 11 | 44 | 0 | 1 |
| T3+T4 | 5 | 1 | 4 | ||
| Lymph nodes metastasis | |||||
| N0 (negative) | 48 | 10 | 38 | 0.104 | 0.747 |
| N1 (positive) | 12 | 2 | 10 | ||
| UICC stage | |||||
| I+IIA | 45 | 10 | 35 | 0.556 | 0.456 |
| IIB+III | 15 | 2 | 13 | ||
| Pretherapeutic CA19-9 level (U/mL) | |||||
| <37 | 12 | 4 | 8 | 1.667 | 0.197 |
| ≥37 | 48 | 8 | 40 | ||
| Postoperative liver metastasis | |||||
| Negative | 35 | 8 | 27 | 0.429 | 0.513 |
| Positive | 25 | 4 | 21 | ||
Note:*P<0.05, statistically significant.