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. 2020 Nov 2;15(11):e0241580. doi: 10.1371/journal.pone.0241580

Table 1. Clinicopathological characteristics of all patients (N = 1,237).

Factors Variable/group Value/no. of patients
Age (years) Median 69
Range 29–89
Sex Female 581 (47.0%)
Male 656 (53.0%)
Smoking history Never smoked 551 (44.5%)
Past/present smoker 686 (55.5%)
Tumor in left or right lung Left 486 (39.3%)
Right 751 (60.7%)
Tumor in upper lobe or other Upper 688 (55.6%)
Others 549 (44.4%)
Pathological stage I 953 (77.0%)
II 167 (13.5%)
III 117 (9.5%)
Surgical procedure ≥ Lobectomy 963 (77.9%)
Sublobar resection 274 (22.1%)
Tumor histology Sq 171 (13.8%)
Non-Sq 1,066 (86.2%)
Pl No 991 (80.1%)
Yes 246 (19.9%)
Ly No 1,120 (90.5%)
Yes 117 (9.5%)
V No 987 (79.8%)
Yes 250 (20.2%)
Adjuvant chemotherapy No 983 (79.5%)
Yes 254 (20.5%)
EGFR statusa Wild-type 267 (54.8%)
Mutant-type 220 (45.2%)
Alb (g/dL) Mean 4.2
Range 2.2–5.3
CRP (mg/dL) Mean 0.38
Range 0.01–40.7
LDH (U/L) Mean 198
Range 78–548
NLR Mean 2.46
Range 0.40–22.83
LMR Mean 5.45
Range 0.37–20.94
PLR Mean 143
Range 21–646
dNLR Mean 1.79
Range 0.23–14.87

a Data only available for 487 patients.

Alb, albumin; CRP, C-reactive protein; dNLR, derived neutrophil-lymphocyte ratio; EGFR, epidermal growth factor receptor; LDH, lactate dehydrogenase; LMR, lymphocyte-monocyte ratio; Ly, lymphatic invasion; NLR, neutrophil-lymphocyte ratio; Pl, pleural invasion; PLR, platelet-lymphocyte ratio; Sq, squamous cell carcinoma; V, vascular invasion.