Table 1. Nonsense mutations and their predicted functions in gallbladder isolates.

Position in CT18	S/NS	Gene	Product	Functional class	GB005	GB026	GB044	GB076	GB125	GB169	GB199	GB266	GB281	GB335	GB368	GB387	GB441	GB580	GB705
239853‥241370	STOP	STY0230	Deoxyguanosine-triphosphate trophosphohydrolase	Central intermediary metabolism							E496*
378398‥378796	STOP	STY0368	probable secreted protein	membrane lipoprotein									C46*
598006‥600618	STOP	fimD	outer membrane usher protein FimD precursor	surface structure														Q386*
1457973‥1458758	STOP	STY1502	probable secreted protein	membrane lipoprotein										W162*
complement (1721748‥1722089)	STOP	STY1802	osmotically inducible lipoprotein E precursor	unknown						Q99*
complement (2513933‥2514808)	STOP	STY2679	sulphate transport system permease protein CysW	transport anion		W175*
complement (2629668‥2631983)	STOP	pbpC	pencillin binding protein 1C	murein sacculus peptidoglycan			Q246*
complement (2915077‥2916069)	STOP	rpoS	RNA polymerase sigma subunit RpoS	broad regulatory function					W247*
complement (3601247‥3603091)	STOP	STY3744	vitamin B12 receptor protein	cell envelope											W33*
3795271‥3796734	STOP	STY3932	putative membrane transport protein	transport/binding protein					Q15*
complement (4037181‥4038752)	STOP	STY4178	Conserved hypothetical protein	hypothetical protein											W413*
4123472‥4125214	STOP	ggt	gamma-glutamyltranspeptidase precursor	thioredoxin											Q105*
4307686‥4308996	STOP	STY4438	putative exported protein	membrane lipoprotein														W184*
4442121‥4444211	STOP	STY4562	hypothetical protein	SPI-7								W234*				W234*
4593908‥4595071	STOP	yjfC	conserved hypothetical protein	hypothetical protein		W9*

* mutations generating a stop codon