Skip to main content
. Author manuscript; available in PMC: 2020 Nov 2.
Published in final edited form as: J Am Chem Soc. 2020 Jul 1;142(28):12394–12399. doi: 10.1021/jacs.0c04725

Scheme 2. Substrate Scope of Diarylcarbene Insertion into Si–H Bondsa.

Scheme 2.

aReaction conditions: hydrazone (0.2 mmol), MnO2 (3.5 equiv), MgSO4, DCM, rt, 5–6 h; then PhMe2SiH (1.2 equiv), C2 (0.1 mol %), DCM, 0 °C. Isolated yields were given. The ee values were determined by chiral HPLC analysis. bDimethylchlorosilane was used and the hydrolysis product was isolated after workup.