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. 2020 Oct 29;13:545–555. doi: 10.2147/JAA.S272681

Table 3.

Adjusted Incremental Direct Medical Costs per Person per Year by Severity of Asthma, 2010–2017†

Asthma (n = 13,732) vs No Asthma (n = 160,805) Mild Asthma (n = 10,586) vs No Asthma Moderate Asthma (n = 3048) vs No Asthma Severe Asthma (n = 98) vs No Asthma Moderate Asthma vs Mild Asthma Severe Asthma vs Mild Asthma
Total costs $4333 (3120, 5546)* $3305 (1780, 4831)* $7250 (6028, 8472)* $9175 (5362, 12,987)* $5131 (3797, 6465)* $8614 (4141, 13,087)*
Outpatient visits $946 (747, 1145)* $822 (615, 1029)* $1274 (789, 1760)* $2236 (1013, 3458)* $604 (139, 1068)* $2001 (470, 3532)*
ED visits $140 (107, 174)* $134 (98, 170)* $155 (83, 227)* $259 (−13, 531) $40 (−47, 128) $184 (−149, 518)
Hospitalizations $578 (304, 852)* $222 (−53, 497) $1649 (910, 2389)* $841 (−1265, 2947) $1935 (763, 3108)* $568 (−2077, 3213)
Prescription drugs $2975 (1858, 4092)* $2105 (733, 3476)* $5420 (4760, 6080)* $6966 (4017, 9914)* $3805 (3023, 4586)* $6479 (2886, 10,071)*
Others $31 (19, 43)* $25 (11, 38)* $46 (18, 75)* $140 (17, 263)* $28 (−3, 59) $134 (−7, 275)

Notes: †Data are presented as mean (95% CI). A generalized linear model (gamma distribution with log link function) was used to adjust for age, sex, race, ethnicity, region, marital status, income, insurance, smoking, and Charlson Comorbidity Index. *P < 0.05.

Abbreviations: ED, emergency department, CI, confidence interval.