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. 2020 Oct 29;7:257–269. doi: 10.2147/JHC.S271091

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© 2020 Tang et al.

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HBV-miR-3 downregulates PTEN protein expression. (A) Wild-type and mutant fragments of the 3ʹ-UTR of PTEN. (B) Luciferase activity of cells transfected with HBV-miR-3 and the wild-type or mutant fragment of the 3ʹ-UTR of PTEN. (C, E, and G) HBV-miR-3 inhibits PTEN protein expression in HepG2 cells in a dose-dependent manner. (D, F, and H) The antagomir of HBV-miR-3 upregulates PTEN protein expression in HepAD38 cells in a dose-dependent manner.