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Progression to severe NPDR or PDR over 5 years.
Note: Patients with mild or moderate NPDR were censored at the first incidence of diabetic macular edema, or first record of treatment with anti-vascular endothelial growth factor agents, laser photocoagulation, or intravitreal steroids.
Abbreviations: NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy.
