Table 4.

Sites of recurrence and treatment of recurrence patients and post‐recurrence cure patients

		Treatment
		Radical local treatment
Initial recurrence site	Number of patients	Resection	Resection with radiation therapy	Radiation therapy	Others	Chemotherapy	Best supportive care
Systemic recurrence	407 (19) †	37 (6)	13 (2)	187 (11)	2	91	77
Single organ	241 (18)	31 (6)	7 (2)	113 (10)	2	47	41
Adrenal grand	6			2		4
Bone	43 (1)	2	1	33 (1)		4	3
Brain	65 (8)	5 (1)	3 (1)	56 (6)			1
Liver	6	3				1	2
Lung	92 (7)	17 (5)		11 (2)	2	33	29
Lymph node (Extrathoracic)	13 (2)		1 (1)	8 (1)		3	1
Others	16	4	2	3		2	5
Multiple organs	166 (1)	6	6	74 (1)		44	36
Locoregional recurrence	128 (5)	14 (1)	2	58 (4)	2	29	23
Single organ	112	13	2	51	2	24	20
Lung	49 (2)	12 (1)	1	13 (1)	2	13	8
Lymph node	35 (3)		1	22 (3)		7	5
Pleura	19	1		9		2	7
Trachea	9			7		2
Multiple organs	16	1		7		5	3

^†Numbers in parentheses are post‐recurrence cure patients.