Table 1.
The clinical characteristics of the included studies.
| First author | Study period, all in 2020 | Affiliation | modality (n) | image analysis (experience) | Number of patients with neuroimaging | sex, male (%) | Age, mean ± SD/median (range) | study design | Multicenter study | microbleed | Acute/subacute infarct | non-traumatic ICH | Encephalitis/encephalopathy |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fitsiori | NR | University Hospitals of Geneva and Faculty of Medicine of Geneva, Geneva | MRI | 2 neuroradiologists (NR) | 9 | 7 (77.8) | 67.7 ± 9 | retrospective | no | 9 | 2 | 0 | 0 |
| Chougar | March 23 - May 7 | Pitie-Salpetrier Hospital, Paris | MRI | 2 neuroradiologists (NR) | 73 | 48 (65.8) | 58.5 ± 15.6 | retrospective | no | 8 | 17 | 0 | 12 |
| Xiong | January 18 - March 20 | 56 hospitals in Hubei and Sichuan | CT | NR | 28 | NR | NR | retrospective | yes | NR | 10 | 0 | 0 |
| Helms | March 3 - April 3 | Strasbourg, France | MRI | NR | 13 | NR | median, 63 | retrospective | yes | 0 | 3 | 0 | 8 |
| Paterson | April 9 - May 15 | University College London, Queen Square Institute of Neurology, London | MRI (13); CT (3) | NR | 16 | 9 (56.3) | 58.8 ± 12.5 | retrospective | yes | 4 | 8 | 0 | 11 |
| Coolen | 3/31−4/24 | CUB Hôpital Erasme, Brussels | MRI | 3 neuroradiologists (NR) | 19 | 14 (73.7) | mean, 77 (49–94) | prospective | no | 2 | 0 | 1 | 2 |
| Jain | March 1 - April 13 | New York University Langone Health | MRI (48); CT (323 one examination; 131 > 1 examinations) | 4 neuroradiologists (fellowship-trained) | 454 | 275 (60.7) | median, 64 | retrospective | yes | 0 | 26 | 0 | 1 |
| Radmanesh | April 5 - April 25 | NYU Langone Medical Centers | MRI | 2 neuroradiologist2 (6 and 9 years of experience) | 27 | 9 of 11 reported (81.8) | 53 (38–64) (11 patients in ICU) | retrospective | no | 7 | 11 | 4 | 5 |
| Hernández-Fernández | March 1 - April 19 | Hospital Universitario de Albacete, Castilla-La Mancha, Spain | CT (23) / both CT and MRI (6) | 1 neuroradiologist (NR) | 23 | 18 (78.3) | 66.8 | retrospective | no | 4 | 17 | 5 | 1 |
| Kremer | March 23 - April 27 | 16 Hospitals in France | MRI | 3 neuroradiologists (9, 20, 25 years of experience) | 37 | 30 (81.1) | 61 ± 12 | retrospective | yes | 9 | NR | 20 | 27 |
| Kandemirli | March 1 - April 18 | 8 Hospitals in Istanbul, Turkey | MRI | 2 neuroradiologists (both, 29 years of experience) | 27 | 21 (77.8) | 63 (34–87) | retrospective | yes | 0 | 1 | 1 | 12 |
| Radmanesh | March 1 - March 31 | NYU Langone Medical Centers | CT (207) / MRI (11) / both CT and MRI (24) | 1 neuroradiologist (6 years of experience) | 242 | 150 (62) | 68.7 ± 16.5 | retrospective | no | 134 | 13 | 11 | 26 |
| D'Amore | February 21 - May 21 | Hospital of Circolo and Macchi Foundation, Varese, Lombardia, Italy | CT (27) / both CT and MRI (4) | 3 neuroradiologists (6, 7, 10 years of experience) | 27 | 7 (46.7) | mean 68 (21–88) | retrospective | no | 0 | 6 | 4 | 2 |
| Klironomos | March 2 - May 24 | Department of Neuroradiology, Karolinska University Hospital | CT (174) / MRI (43) (both CT and MRI, 32) | 11 neuroradiologists, 1 radiology resident (mean ± SD, 11.5 ± 5.7 years of experience) | 185 | 138 (74.6) | 62 ± 14 | retrospective | no | 29 | 25 | 27 | 31 |
| Yoon | March 3 - May 6 | Department of Radiology, Massachusetts General Hospital | CT (141) / MRI (21) / both CT and MRI (31) | 2 neuroradiologists (NR) | 150 | 98 (65.3) | 63.6 ± 16 | retrospective | no | 7 | 13 | 2 | 7 |
| Sheth | October 30, 2019 – May 20, 2020 | Department of Neurology, Yale University School of Medicine | Portable MRI (20) | 1 neuroradiologist (NR) | 20 | 17 (85) | 60 ± 8 | Prospective | No | 0 | 3 | 1 | 3 |
| Shahjouei | March 27 – May 1 | 99 tertiary centers in 11 countries | CT or MRI | Local radiologists (NR) | 156 | 109 (70) | 66 ± 15 | Retrospective | Yes | 0 | 123 | 27 | 0 |
| Sawlani | March 1 - May 31 | Queen Elizabeth Hospital Birmingham | CT (172) / MRI (36) | 2 neuroradiologists (NR) | 167 | NR | NR | Retrospective | No | 12 | 21 | 3 | 0 |
| Lin | March 4 - May 9 | academic quaternary-care center and affliated community hospital | CT (269) / MRI (51) (both, 42) | 2 neuroradiologists (10 years) | 278 | 165 (59) | 64 (50−75) | Retrospective | No | 3 | 31 | 10 | 0 |
| Freeman | March 1 - June 18 | Perelman School of Medicine at the University of Pennsylvania | MRI | 3 neuroradiologists (NR) | 59 | NR | Nr | Retrospective | No | 2 | 10 | 0 | 0 |
| Agarwal | March 1 - May 10 | 3 tertial care hospitals of an academic medical center | MRI | 2 neuroradiologist (fellow) | 1115 | 82 (71.3) | NR | Retrospective | Yes | 25 | 47 | 0 |
NR = not reported; NA = not applicable; SD = standard deviation; DWI = diffusion-weighted imaging; T1WI = T1-weighted imaging; T2WI = T2-weighted imaging; CE-T1WI = contrast-enhanced T1-weighted imaging; FLAIR = fluid attenuated inversion recovery; SWI = susceptibility-weighted imaging.