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. 2020 Aug 5;10(10):1966–1976. doi: 10.1016/j.apsb.2020.07.019

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Biodistribution and targeting delivery study. (A) In vivo imaging of colitis mice. (B) Statistical analysis of in vivo radiant efficiency. (C) In vitro radiant efficiency of the major organs and colons. (D) Statistical analysis of ex vivo colonic radiant efficiency. (E) M1Φ-tageting evaluation by detecting the M1 that captured Cy5 labeled liposomes in colitis tissues, indicated by population of CD86⁺/Cy5⁺ macrophages detected by flow cytometry (F) Statistical analysis of CD86⁺Cy5⁺ macrophage population. Data are expressed as mean ± SD (n = 3). **P < 0.01, ***P < 0.001.