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Compound 2c induced significant degradation of IDO1. (A) HeLa cells were pre-treated with 2c (5 μmol/L) and INF-γ (5 ng/mL) for 24 h before immunostaining. Scale bar, 20 μm. (B) The results of flow cytometry analysis that IFN-γ induced a significant increase of IDO1, and 2c reduced IDO1 to a level comparable to the control. Scale bar: 20 μm.
