Table 3.

Chemical structures, regulation mechanisms and in vitro/in vivo activities of potential HSP60 inhibitors.

Name	Year	Structure	Mechanism	In vitro assay	In vivo efficacy	Ref.
BF844	2016		Unknown	–	NDa	124
Phenoxyacetanilide	2010		Directly binding to HSP60	IC50 = 0.74 μmol/L	NDa	125
KHS-101	2018		Unknown	–	NDa	126
Suvanine	2012		Directly binding to HSP60	IC50 = 0.6 μmol/L	NDa	127
Epolactaene	2005		Covalently binding to HSP60 Cys442	Low μmol/L	NDa	128
Myrtucommulone	2017		Directly binding to HSP60	Micromolar level	NDa	129

^aNot determined. –Not applicable.