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. 2019 Jun 26;10(10):1977–1988. doi: 10.1016/j.apsb.2019.06.008

Figure 6.

Figure 6

In vivo anti-metastasis treatment. (A) The number of 4T1 metastases nodules on the lung surface (means ± SD, n = 5; ∗P＜0.05,∗∗P＜0.01 and ∗∗∗P＜0.001). (B) Body weight of BALB/c mice during the therapies (means ± SD, n = 5). (C) Images of lungs, HE staining for lungs (the scale bar represents 100 μm) and immunohistochemical analysis of MMP-9 staining for lungs (the scale bar represents 25 μm) after treatment with PBS, LMWH, free GEM, GTT or GLT, respectively, by intravenous injection. Black arrows indicate the secreted MMP-9.