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. 2019 Jun 26;10(10):1977–1988. doi: 10.1016/j.apsb.2019.06.008

Table 1.

Pharmacokinetic parameters after intravenous administration of GEM and GLT (n = 3).

Parameter t1/2 (h) V1 (L/kg) CL (L/h/kg) AUC0‒t (mg·h/L) AUC0‒∞ (mg·h/L)
GEM 0.615±0.037 0.027±0.015 0.340±0.085 10.881±2.552 11.241±2.816
GLT 7.632±1.039 0.29±0.056 0.052±0.007 62.648±15.722 82.692±10.514

GEM, gemcitabine; GLT, GEM-TOS co-assembly with LMWH-TOS.