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. 2020 Oct 20;40(10):1422–1431. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2020.10.07

1.

差异表达基因的GO富集分析

Gene ontology analysis of the DEGs

Expression Category ID Term n P
Up-Regulated BP GO:0140014 Mitotic nuclear division 17 < 0.01
BP GO:0000280 Nuclear division 19 < 0.01
BP GO:0048285 Organelle fission 19 < 0.01
BP GO:0007088 Regulation of mitotic nuclear division 12 < 0.01
BP GO:1902850 Microtubule cytoskeleton organization involved in mitosis 11 < 0.01
BP GO:0051783 Regulation of nuclear division 12 < 0.01
CC GO:0005819 Spindle 14 < 0.01
CC GO:0000779 Condensed chromosome, centromeric region 10 < 0.01
CC GO:0000776 Kinetochore 10 < 0.01
CC GO:0000775 Chromosome, centromeric region 11 < 0.01
CC GO:0000777 Condensed chromosome kinetochore 9 < 0.01
CC GO:0000922 Spindle pole 10 < 0.01
MF GO:0004222 Metalloendopeptidase activity 5 < 0.01
MF GO:0005201 Extracellular matrix structural constituent 5 < 0.01
MF GO:0030020 Extracellular matrix structural constituent conferring tensile strength 3 < 0.01
MF GO:0008237 Metallopeptidase activity 5 < 0.01
MF GO:0005539 Glycosaminoglycan binding 5 < 0.01
MF GO:0035173 Histone kinase activity 2 < 0.01
Down-Regulated BP GO:0031589 Cell-substrate adhesion 18 < 0.01
BP GO:0001570 Vasculogenesis 9 < 0.01
BP GO:0003018 Vascular process in circulatory system 12 < 0.01
BP GO:0010810 Regulation of cell-substrate adhesion 13 < 0.01
BP GO:0001667 Ameboidal-type cell migration 17 < 0.01
BP GO:0043062 Extracellular structure organization 16 < 0.01
CC GO:0044449 Contractile fiber part 10 < 0.01
CC GO:0001725 Stress fiber 6 < 0.01
CC GO:0097517 Contractile actin filament bundle 6 < 0.01
CC GO:0043292 Contractile fiber 10 < 0.01
CC GO:0032432 Actin filament bundle 6 < 0.01
CC GO:0042641 Actomyosin 6 < 0.01
MF GO:0005539 Glycosaminoglycan binding 11 < 0.01
MF GO:0005201 Extracellular matrix structural constituent 9 < 0.01
MF GO:1901681 Sulfur compound binding 10 < 0.01
MF GO:0008201 Heparin binding 8 < 0.01
MF GO:0070696 Transmembrane receptor protein serine/threonine kinase binding 3 < 0.01
MF GO:0044325 Ion channel binding 6 < 0.01