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. 2020 Oct 29;12:10749–10762. doi: 10.2147/CMAR.S263619

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© 2020 Liu et al.

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miR-498 overexpression inhibits the malignant feature of HCC cells. (A) The level of miR-498 was examined via RT-qPCR in miR-498 mimic-transfected or miR-NC-transfected HuH7 and SNU-182 cells. (B and C) The proliferation and apoptosis of miR-498-overexpressed HuH7 and SNU-182 cells were analyzed via the CCK-8 assay and flow cytometric analysis, respectively. (D and E) Transwell cell migration and invasion assays were used to examine the migration and invasion of HuH7 and SNU-182 cells after miR-498 upregulation (x200 magnification). *P < 0.05 and **P < 0.01.