Table 2.
GEOS Single-Variant All-Stroke Meta-Analysis Results (Fixed-Effect Model).
| CHR | BP | SNP (type) | Gene | EA | OR | EAF (AA;Eur;Ref*) | P-value |
|---|---|---|---|---|---|---|---|
| 1 | 55304970 | rs7549251 (intron) | LEXM (C1orf177) | G | 1.50 | 0.38;0.61;0.44 | 4.08E-07 |
| 4 | 184612553 | rs67383011 (missense) | TRAPC11 | C | 0.50 | 0.10;0.05;0.08 | 5.19E-06 |
| 7 | 12406989 | rs6460939 (missense) | VWDE | G | 1.41 | 0.46;0.55;0.49 | 8.79E-06 |
| 8 | 120052238 | rs6993813 (intron) | COLEC10 | T | 1.41 | 0.47;0.25;0.41 | 2.60E-05 |
| 9 | 139111870 | rs7849585 (intron) | QSOX2 | G | 0.71 | 0.67;0.24;0.55 | 5.32E-05 |
*
Ref indicates effect-allele-frequency in gnomAD-database4. EA=effect-allele and EAF=effect-allele-frequency.