Table 1.
Baseline characteristics + laboratory parameters and miRNA levels at baseline/1 h after parabolic flight/24 h after parabolic flight.
| Parameter | Timepoint | Median | IQR |
|---|---|---|---|
| Male/female sex n (%) | Baseline | 4 (50)/4 (50) | |
| Age (years) | Baseline | 24.5 | 12.5 |
| Weight (kg) | Baseline | 80.5 | 27 |
| Height (cm) | Baseline | 177.5 | 17 |
| Creatinine (µmol/l) | Baseline | 72.93 | 7.52 |
| 1 h after parabolic flight | 66.3 | 8.18 | |
| 24 h after parabolic flight | 67.63 | 13.26 | |
| GFR (ml/min/1,73 m²) | Baseline | 93.95 | 26.4 |
| 1 h after parabolic flight | 106.3 | 34.45 | |
| 24 h after parabolic flight | 106.15 | 16.35 | |
| CRP (mg/l) | Baseline | 2 | 1.75 |
| 1 h after parabolic flight | 1.5 | 1.75 | |
| 24 h after parabolic flight | 1.5 | 1.75 | |
| BNP (pg/ml) | Baseline | 9.5 | 2.75 |
| 1 h after parabolic flight | 10 | 3 | |
| 24 h after parabolic flight | 9 | 9 | |
| CK (U/l) | Baseline | 113 | 130.75 |
| 1 h after parabolic flight | 120 | 121.5 | |
| 24 h after parabolic flight | 141 | 125.5 | |
| Myoglobin (µg/l) | Baseline | 33.5 | 24.6 |
| 1 h after parabolic flight | 40.35 | 43.7 | |
| 24 h after parabolic flight | 30.3 | 47.2 | |
| mir-486-3p (TPM) | Baseline | 807.113.74 | 600.797.18 |
| 1 h after parabolic flight | 503.349.41 | 331.243.28 | |
| 24 h after parabolic flight | 1.067.561.35 | 629.299.14 | |
| mir-24-3p (TPM) | Baseline | 414.17 | 180.57 |
| 1 h after parabolic flight | 554.23 | 211.55 | |
| 24 h after parabolic flight | 318.63 | 99.47 | |
| mir-223-3p (TPM) | Baseline | 705.58 | 972.14 |
| 1 h after parabolic flight | 665.82 | 1082.92 | |
| 24 h after parabolic flight | 182.72 | 170.26 | |
| mir-941 (TPM) | Baseline | 953.54 | 447.29 |
| 1 h after parabolic flight | 884.13 | 702.23 | |
| 24 h after parabolic flight | 546.08 | 350.6 |
µmol/l micromole/liter, ml/min/1.73 m²: milliliter/minute/1.73 square meters, mg/l milligram/liter, pg/ml picogram/milliliter, U/l units/litre, µg/l microgram/liter, TPM tags per million.