(10 Hz, 2 ms, 15 mA, pulse train protocol) as monitored by manometry in anesthetized pigs (n=2–6 each). A) Representative trace of direct distal colon stimulation. B) Pressure map representation. Channels represent the position of the different manometry probes in the different colonic parts (P: proximal, T: transverse and D: distal). C) Frequency power spectrum in the proximal, transverse and distal colon in response to direct distal stimulation (cumulative recordings from 4 probes per colonic region in n=2–6 pigs). Direct ES of the distal colon induced a trend for increase in the power of the 1–12 cpm frequencies in distal colon exclusively. Data are mean ± SEM.