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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Neurogastroenterol Motil. 2020 Jun 23;32(11):e13925. doi: 10.1111/nmo.13925

Figure 6. Influence of different protocols of electrical stimulation of the abdominal vagus nerve, celiac branch on colonic motility in anesthetized pigs.

Figure 6.

Pressure map of A) pulse train, 2 Hz, 0.3 ms, 5 mA, 10 min, without anodal block; B) pulse train, 2 Hz, 4 ms, 5 mA, 10 min, without anodal block; C) pulse train, 2 Hz, 4 ms, 5 mA, 10 min, with afferent anodal block 200 Hz, 2 ms, 0.1 mA. Channels represent the position of the different manometry probes in the different colonic parts (P: proximal, T: transverse and D: distal). Traces show the baseline response (15 min), stimulation (15 min) and post stimulation (30 min) periods. Data are mean ± SEM of recordings from n=7–14 pigs. D) Motility index changes (mean change from baseline %) in response to celiac branch vagus nerve stimulation (2 Hz, 5 mA) at pulse width of 0.3 ms (white bars), 4 ms (grey bars) and 4 ms with anodal block (black bars), during the stimulation (15 min) and post stimulation (30 min) in proximal, transverse and distal (n=7–14) regions. Data are mean ± SEM, Wilcoxon paired or Mann-Whitney unpaired t tests, *p<0.05, **p<0.01 vs baseline, +p<0.05 vs stimulation in respective groups.