Table 1.
Demographic and collection characteristics for first time United States BM donors between 2006 and 2017
| Variable |
No Autologous Blood Transfusion N (%) |
Autologous Blood Transfusion N (%) |
p-value |
|---|---|---|---|
| Number of donors | 2813 | 4211 | 0.001 |
| Autologous blood units transfused | |||
| 1 | 0 | 2957 (70) | |
| 2 | 0 | 1236 (29) | |
| 3 | 0 | 18 (<1) | |
| Donor age at donation | 0.001 | ||
| 18 to 29 | 1408 (50) | 1926 (46) | |
| 30 to 39 | 784 (28) | 1215 (29) | |
| 40 to 49 | 471 (17) | 791 (19) | |
| 50+ | 150 (5) | 279 (7) | |
| Median (Range) | 30 (19-61) | 31 (19-61) | <0.001 |
| Sex | 0.002 | ||
| Female | 1132 (40) | 1539 (37) | |
| Male | 1681 (60) | 2672 (63) | |
| Race | 0.005 | ||
| Caucasian | 1755 (62) | 2735 (65) | |
| Hispanic | 381 (14) | 547 (13) | |
| Black / African American | 194 (7) | 301 (7) | |
| Asian / Pacific Islander | 189 (7) | 226 (5) | |
| American Indian / Alaska Native | 34 (1) | 37 (1) | |
| Other / Multiple Race | 250 (9) | 328 (8) | |
| Decline / Unknown | 10 (<1) | 37 (1) | |
| Donor Body Mass Index BMI | 0.001 | ||
| Underweight (<18.5) | 20 (1) | 18 (<1) | |
| Normal (18.5-24.9) | 967 (34) | 1325 (31) | |
| Overweight (25-29.9) | 953 (34) | 1605 (38) | |
| Obese (≥30) | 872 (31) | 1263 (30) | |
| Unknown | 1 (N/A) | 0 (N/A) | |
| Donor Weight, kg | |||
| Median (Range) | 81 (42-155) | 82 (40-164) | 0.026 |
| Hemoglobin at baseline, g/dL | |||
| N Eval | 2813 | 4211 | |
| Median (1st to 99th percentile) | 15 (11.1-17.4) | 15 (11.5-17.3) | 0.631 |
| Hemoglobin pre-BM harvest, g/dL | |||
| N Eval | 2775 | 4154 | |
| Median (1st to 99th percentile) | 14 (10.6-17.2) | 14 (9.9-16.3) | <0.001 |
| Hemoglobin post-BM harvest, pre-transfusion, g/dL | |||
| N Eval | 0 | 1081 | |
| Median (1st to 99th percentile) | 11 (7-15) | ||
| Hemoglobin post-BM harvest, post-transfusion, g/dL | |||
| N Eval | 0 | 3055 | |
| Median (1st to 99th percentile) | 11 (8-15) | ||
| Hemoglobin post-BM harvest, no transfusion, g/dL | |||
| N Eval | 2471 | 0 | |
| Median (1st to 99th percentile) | 12 (8-15) | ||
| Collection volume per kg of donor weight | <0.001 | ||
| <10 mL/kg | 1540 (55) | 550 (13) | |
| 10 to <15 mL/kg | 729 (26) | 1453 (35) | |
| 15 to <20 mL/kg | 391 (14) | 1720 (41) | |
| ≥ 20 mL /kg | 130 (5) | 442 (11) | |
| Unknown | 23 (N/A) | 46 (N/A) | |
| Collection volume per donor volume, % | <0.001 | ||
| N Eval | 2791 | 4165 | |
| Median (Range) | 15 (2-45) | 25 (5-46) | |
| TNC in the product (x108) | <0.001 | ||
| N Eval | 2800 | 4188 | |
| Median (1st to 99th percentile) | 175 (47-474) | 260 (106-525) | |
| TNC in the product per kg recipient weight (x108) | <0.001 | ||
| N Eval | 1394 | 2150 | |
| Median (1St to 99th percentile) | 5.6 (1.4-30.1) | 4.0 (1.4-21.7) | |
| Type of anesthesia | |||
| Epidural | 16 (<1) | 16 (<1) | <0.001 |
| General | 2729 (97) | 4155 (99) | |
| Local | 6 (<1) | 3 (<1) | |
| Spinal | 61 (2) | 35 (<1) | |
| Duration of anesthesia in minutes | <0.001 | ||
| N Eval | 1515 | 3018 | |
| Median (Range) | 80 (25-216) | 98 (25-217) | |
| Duration of collection in minutes | <0.001 | ||
| N Eval | 1524 | 3051 | |
| Median (Range) | 37 (4-210) | 57 (2-221) | |
| Year of collection | <0.001 | ||
| 2006 | 139 (26.6%) | 330 (70.4%) | |
| 2007 | 124 (26.1%) | 352 (73.9%) | |
| 2008 | 157 (30.4%) | 359 (69.6%) | |
| 2009 | 168 (33.5%) | 333 (66.5%) | |
| 2010 | 179 (33.3%) | 358 (66.7%) | |
| 2011 | 204 (34.6%) | 385 (65.4%) | |
| 2012 | 267 (36.8%) | 459 (63.2%) | |
| 2013 | 264 (37.7%) | 436 (62.3%) | |
| 2014 | 262 (39.5%) | 402 (60.5%) | |
| 2015 | 258 (43.7%) | 332 (56.3%) | |
| 2016 | 387 (60.8%) | 250 (39.2%) | |
| 2017 | 404 (65.3%) | 215 (34.7%) |