Table 6.

Similarities and differences of ABPA in patients with cystic fibrosis or asthma.

	ABPA in CF	ABPA in Asthma
Childhood onset	Common	Uncommon
Sex	Male/Female=1	Male/Female=1
Clinic	Pulmonary exacerbation of CF	Worsening of asthmatic symptoms
Mucus Production	Increased, brown-black	New, brown-black
Clubbing	Common	Rare
Eosinophilia	Uncommon	Common
Total IgE >1,000 IU/mL	+	+
Specific serologic test	rAsp f6 specific IgE	Combination of rAsp f4 and f6 specific IgE
Aspergillus skin prick test	+	+
Concomitant bacterial infections	Common	Uncommon
Bronchiectasis	Central, but generally extensive	Central
Transient pulmonary opacities	+	+
High attenuation mucus plugs on chest CT	+	+

ABPA, allergic bronchopulmonary aspergillosis; CF, cystic fibrosis; IgE, immunoglobulin E; rAsp, recombinant Aspergillus fumigatus antigens.