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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Kidney Int. 2020 Jun 25;98(5):1160–1173. doi: 10.1016/j.kint.2020.05.052

Figure 4. Increased senescent genes in aged podocytes.

Figure 4.

A.) Heatmap of top differentially expressed senescence genes in aged vs. young podocytes (adjusted p-value <0.01, >3 fold change in either direction, expressed above 4 RPKM in either condition).

B.) Heatmap of all differentially Senescence-Associated Secretory Phenotype (SASP) genes (adjusted p-value <0.05, fold change >2, expressed above 4 RPKM in either condition) showed that chemokines and matrix metalloproteases are enriched in aged podocytes.