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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Abdom Radiol (NY). 2020 Jul 31;45(11):3545–3556. doi: 10.1007/s00261-020-02677-2

Figure 1.

Figure 1.

Molecular MRI of liver fibrosis using the type I collagen-targeted probe EP-3533 in the rat diethylnitrosamine (DEN) model. Inversion recovery MRI of the rat liver before and 40 min after injection of 20 μmol/kg EP-3533; S, stomach; L, liver. The inversion time was chosen to minimize liver signal prior to probe injection. Post-injection, there is a higher signal in the liver of the DEN-treated animal compared to control.