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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Abdom Radiol (NY). 2020 Jul 31;45(11):3545–3556. doi: 10.1007/s00261-020-02677-2

Figure 6.

Figure 6.

Multi-parametric MRI with collagen targeted EP-3533 probe in controls, rats fed with choline-deficient, L-amino acid-defined, high-fat diet (CDAHFD) for 6 weeks or 9 weeks, and rats had that received 6 weeks of CDAHFD subsequently either switched back to standard chow for 3 weeks (CDAHFD/SD) or underwent 3 weeks of daily oral gavage of Elafibranor while continuing on CDAHFD (CDAHFD+ELA). (A) Representative axial R1 maps of the liver for each group at baseline and after injection of EP-3533. (B) Representative ΔR1 maps from each group showing the uptake of Gd-Hyd.