Figure 4. Pharmacological activation of mast cells after aneurysm formation promoted aneurysmal rupture without affecting the aneurysmal formation.
A. Time window of the mast cell activation treatment by C48/80. B. No difference in the incidence of aneurysm between C48/80-treated and vehicle-treated mice. C. Aneurysm rupture rate was significantly increased in C48/80-treated as compared to vehicle-treated mice. * P < 0.05.