Table 1.
Demographic and immunovirologic characteristics of the study population.
pHIVAd | HIVagematch | HIVOA | F/χ2 | p | |
---|---|---|---|---|---|
Age in years (mean/SEM/range) | 24.7 (1.1)a Range 21-30 | 27.2 (1.1)b Range 20-32 | 56.6 (1.1)a,b Range 50-67 | 240.7 | <0.001 |
Sex (% male) | 15%a | 92%a,b | 15%b | 21.2 | <0.001 |
Ethnicity (% Hispanic*) | 31% | 38% | 54% | 1.5 | 0.476 |
Race (%) | 9.0 | 0.173 | |||
African American | 92% | 77% | 54% | ||
Caucasian | 0% | 8% | 31% | ||
Multiracial | 8% | 8% | 15% | ||
Other/unreported | 0% | 8% | 0% | ||
Years education (mean/SEM/range) | 13.1 (0.6)a Range 11-16 | 13.5 (0.6)b Range 8-16 | 10.1 (0.6)a,b Range 8-14 | 10.4 | <0.001 |
Reading level (grade level; mean/SEM/range)** | 8.9 (0.7)a Range 4.2-13.0 | 11.8 (0.7)a,b Range 9.6-13.0 | 9.4 (0.7)b Range 4.2-13.0 | 4.5 | 0.018*** |
Years with HIV (mean/SEM/range) | 24.7 (0.8)a | 4.8 (0.8)a,b | 24.0 (0.8)b | 208.5 | <0.001 |
Age infected (mean/SEM/range) | 0.0 (1.3)a,b Range 0-0 | 22.5 (1.3)a,c Range 13-29 | 32.6 (1.3)b,c Range 23-45 | 167.9 | <0.001 |
Current CD4 T cell count (cells/mm3; median/IQR) | 423 [177,555]a | 620 [486, 958]a | 632 [124, 709] | 6.4 | 0.040*** |
Nadir CD4 T cell count (cells/mm3; median/IQR) | 118 [32, 155]a | 406 [252, 591]a,b | 100 [20, 244]b | 14.1 | <0.001 |
Plasma HIV RNA load (log copies/ml; median/IQR) | 1.69 [1.28, 3.98] | 1.28 [1.28, 1.49] | 1.28 [1.28, 2.86] | 3.0 | 0.222 |
For each group, n=13. Within rows, means with the same superscript letter are significantly different at p<0.05. ANOVA with F ratio provided for age, years of education, reading grade level, years with HIV, and age at infection; Chi squares with Pearson χ2 provided for sex, ethnicity, and race; Wilcoxon/Kruskall-Wallis tests for current CD4, nadir CD4, and plasma HIV RNA load
Hispanic individuals endorsed African American (n=8), Caucasian (n=4), and multiple or other (n=4) race
Reading grade level was determined by the WRAT-4 reading test.
With Bonferroni correction for multiple comparisons, not significant