Table 3.

Best Response on Pemetrexed and Observation Arm

Best Response	Pemetrexed (N=27)	Observa6on† (N=21)	Total (N=48)
Complete	1 (3.7%)	0 (0%)	1 (2.1%)
Partial	2 (7.4%)	0 (0%)	2 (4.2%)
Stable	12 (44.4%)	14 (66.6%)	26 (54.2%)
Progression	12 (44.4%)	6 (28.6%)	18 (37.5%)
Non CR/ Non PD	0 (0.0%)	1 (4.8%)	1 (2.1%)
Response Rate (95% CI) *	11.1 (2.4, 29.2)	0 (0, 0)	6.3 (1.3, 17.2)

^†One pa6ent’s tumor response is unavailable due to withdrawal of consent for follow-up

^*Fisher’s exact test on response rate between two arms, two-sided: p =0.2460

Abbreviations: Non CR = non complete response; non PD = non progressive disease