Table 2.

Baseline Risk Factors for Incident Glaucoma, eyes with uveitis treated with [fluocinolone acetonide 0.59 mg) Implant or Systemic Therapy in the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study

		Crude			Adjusted*
Risk factor	Comparison	Hazard ratio	95% CI	P-value	Hazard ratio	95% CI	P-value
Design
Treatment group	Implant vs. Systemic	5.8	3.2, 10.5	<0.001	6.3	3.4, 11.8	<0.001
Stratum	Posterior or Panuveitis vs. Intermediate Uveitis	1.15	0.70, 1.89	0.58
Demographics
Age	50+ vs <50 yrs	0.76	0.47, 1.24	0.27
Race	Black vs other	1.28	0.74, 2.23	0.37	1.73	1.01, 2.94	0.04
Sex	Male vs. Female	1.01	0.60, 1.73	0.96
Body mass index	/ kg/m2	0.98	0.95, 1.01	0.16
Baseline use of IOP-lowering medication	Yes vs no	2.19	1.23, 3.88	0.008	2.24	1.24, 4.05	0.008
Eye BL characteristics
Higher intraocular pressure	/ mmHg	1.07	1.01, 1.14	0.02
Larger cup-to-disc ratio	/0.1	1.26	1.05, 1.51	0.02	1.32	1.07, 1.62	0.01
Mean deviation	/dB	0.98	0.95, 1.01	0.26
Bilateral disease	Yes vs. no	0.81	0.40, 1.62	0.54

^*Used multiple imputation for CDR (due to 24% missing data) and forward selection model with probability of entry = 0.05 using candidate set of all baseline risk factors. Baseline intraocular pressure was not selected by forward selection, see Methods). BL=baseline; CI=confidence interval.