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Effect of EGFR2R-lytic hybrid peptide-TDCA-citric acid complex. (A) Measurement of antitumor effect of complex by monitoring tumor size in mice. The complex demonstrated higher tumor inhibition than cationic peptide and S-1 (5-FU oral formulation, positive control). (B) Tight junction opening effect of the complex in Caco-2 cell monolayers. Reproduced, with permission, from reference [126].
