. Author manuscript; available in PMC: 2021 Nov 10.

Published in final edited form as: J Control Release. 2020 Jul 22;327:100–116. doi: 10.1016/j.jconrel.2020.07.034

Table 1.

Selected receptors/transporters used for oral absorption.

Name	Type	Substrates	References
Neonatal Fc receptor (FcRn)	receptor	IgG, albumin	[39]
Folic acid receptor	receptor	Vitamin B9 (folic acid)	[45]
Cubulin	receptor	Intrinsic factor-Vitamin B12	[34]
TfR	receptor	Transferrin	[46]
αvβ3	receptor	iRGD, FQS peptide	[47]
Oligopeptide transporter (PEPT1)	transporter	β-lactam antibiotics, bestatin, etc.	[48]
Organic anion transporter (OAT)	transporter	Bile salts, thyroid hormones, conjugated steroids, etc.	[49]
Monocaboxylate transporter (MCT)	transporter	Atorvastatin, ketoprofen, naproxen, etc.	[50, 51]
Amino acid transporter ATB^0,+	transporter	Valacyclovir, ganciclovir, etc.	[52]
Sodium-dependent glucose transporter (SGLT)	transporter	D-glucose, D-galactose	[31, 53]
Sodium-dependent bile acid transporter (ASBT)	transporter	Bile acid, acyclovir, gabapentin	[54]