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Clinical scores of EAE mice treated in vivo with (A) free PLP139–151 and (B) 4-arm PLP139–151. Treatments were administered subcutaneously on days 4, 7, and 10 with 40 mg/mL mannitol as vehicle. All doses were based on 200 nmol PLP139–151 basis. N=6 for all groups. Data is presented as mean ± SD.
