Table 2.
ECG parameters before (pre) and after (post) treatment with venlafaxine XR.
| Pre-Treatment | Post-treatment | Change from pre- to post-treatment | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ECG parameter | Mean | SD | Min | Max | Mean | SD | Min | Max | Mean | SD | t-value | p-value |
| QTc | 416.5 | 25.4 | 361.9 | 493.2 | 412.8 | 23.8 | 346.0 | 486.9 | − 3.74 | 16.69 | −2.91 | 0.0041 |
| QT | 400.9 | 39.3 | 308 | 496 | 389.8 | 33.1 | 309 | 474 | − 11.11 | 25.88 | −5.58 | <0.0001 |
| QRS width | 90.7 | 18.5 | 65 | 180 | 90.8 | 20.1 | 60 | 192 | 0.16 | 6.71 | 0.31 | 0.7573 |
| PR | 167.5 | 23.6 | 110 | 258 | 164.1 | 24.2 | 110 | 278 | − 3.39 | 11.07 | −3.98 | 0.0001 |
| Heart rate | 69.1 | 13.0 | 45 | 107 | 72.6 | 11.8 | 48 | 106 | 3.55 | 9.74 | 4.74 | <0.0001 |