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. 2020 Oct 20;8:534372. doi: 10.3389/fpubh.2020.534372

Table 3.

Odds ratios for diabetic neuropathy determined by multilevel mixed-effects logistic regression.

Univariate analysis Multivariate analysis
Variable Crude OR (95% CI) P Adjusted OR (95% CI) P
Age, per 5-year increase 1.15 (1.08–1.22) <0.001 1.04 (0.96–1.13) 0.307
Gender (male vs. female) 0.79 (0.65–0.96) 0.017 0.85 (0.65–1.10) 0.214
Location of residence (urban vs. rural) 1.04 (0.74–1.46) 0.819 1.08 (0.70–1.65) 0.739
Marital status (not married vs. married) 1.16 (0.94–1.43) 0.175 0.94 (0.72–1.23) 0.653
Higher education (yes vs. no) 0.66 (0.53–0.82) <0.001 0.77 (0.58–1.01) 0.062
Regular family income (yes vs. no) 0.88 (0.67–1.14) 0.330 1.26 (0.87–1.82) 0.217
Smoking status
  Ever vs. never 1.60 (1.25–2.04) <0.001 1.34 (0.98–1.83) 0.069
  Current vs. never 0.93 (0.69–1.26) 0.649 1.10 (0.76–1.59) 0.602
Higher exercise level (yes vs. no) 0.70 (0.57–0.86) 0.001 0.93 (0.72–1.20) 0.582
Family history of diabetes (yes vs. no) 1.12 (0.91–1.37) 0.291 0.96 (0.75–1.24) 0.759
Duration of diabetes, per 1-year increase 1.08 (1.07–1.10) <0.001 1.08 (1.06–1.09) <0.001
HbA1c, per 1% increase 1.17 (1.11–1.23) <0.001 1.11 (1.05–1.18) <0.001
Hypertension (yes vs. no) 2.13 (1.69–2.68) <0.001 1.58 (1.18–2.12) 0.002
BMI, per 1 kg/m2 increase 1.02 (1.01–1.04) 0.006 1.02 (1.00–1.04) 0.125
Cardiovascular disease 3.00 (2.35–3.84) <0.001 2.07 (1.55–2.78) <0.001
Depressive symptoms (yes vs. no) 2.45 (1.93–3.11) <0.001 1.92 (1.43–2.58) <0.001