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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: FASEB J. 2020 Sep 24;34(11):15417–15430. doi: 10.1096/fj.202001524R

Figure 7. STING agonist 2,3-cGAMP protects the intestines from Citrobacter rodentium infection in vivo.

Figure 7.

WT B6 mice were given 5 × 108 CFU of bacteria via oral garage. The mice were administered daily with 0.5 mg/kg 2’3’-cGAMP or PBS as control. (A) Changes in body weight were monitored daily. (B) Representative histopathology of the colon from WT and STING−/− mice on day 10 post-infection. Scale bar, 300μm. (C) Pathology scores. (D) Fecal colony-forming units (CFU) were quantified on day 7. *p < 0.05. Data were represented as means ± standard deviation. One representative of 2 experiments with similar results was shown.