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. 2020 Nov 3;36(2):176–186. doi: 10.1007/s12250-020-00304-4

Fig. 5.

Fig. 5

Overexpression of KPNA2, KPNA3, KPNA4 restores the MGF360-12L induced IFN-β suppression. (Top) HeLa cells were transfected or co-transfected with pFlag-12L or pMyc-KPNA2, pMyc-KPNA3, pMyc-KPNA4. After transfection 12 h, cells were left untreated or transfected with poly (I:C) (5 µg/mL). After 12 h, the mRNA levels of IFN-β were detected by qPCR. *** P < 0.001 compared to cells transfected with poly (I: C), empty vector or pFlag-12L (n = 3). (Bottom) MGF360-12L expression levels were analyzed by Western blotting.