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. 2020 Oct 20;8:557447. doi: 10.3389/fbioe.2020.557447

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Copyright © 2020 Dawson, Lee, van Rienen and Appali.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Total number of mesenchymal stem cells in the cell culture. (B) Biochemical analysis of the total ALP activity in the cell culture. Total number of hMSCs indicated stem cell proliferation, whereas the total ALP activity indicated the stem cell differentiation. ^*p < 0.05, ^**p < 0.01. Figure obtained with permission from Hess et al. (2012a).