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. 2020 Oct 20;8:557447. doi: 10.3389/fbioe.2020.557447

Figure 6.

Figure 6

The constituents of progressive stem cell differentiation model are (A) Symmetric non-conserved cell division. The division of a stem cell with ALP activity a results in two daughter stem cells, each with ALP activity a. (B)The osteogenic differentiation in instantaneous stem cell differentiation model occurs instantaneously via sudden loss of a cell's ALP activity. Such a process instantaneously gives rise to an osteoblast cell with no ALP activity.