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. 2020 Jul 13;50(5):281–290. doi: 10.5051/jpis.2000120006

Table 5. Pathway analysis with ConsensusPathDB (adjusted P<0.02).

Pathway Source Percentage P value Adj. P (FDR)
Direct p53 effectors PID 6 (4.2%) <0.001 <0.001
E2F transcription factor network PID 4 (5.3%) <0.001 0.002
Regulation of TP53 expression and degradation Wikipathways 2 (50.0%) <0.001 0.002
FOXM1 transcription factor network PID 3 (7.1%) <0.001 0.006
HATs acetylate histones Reactome 4 (2.8%) <0.001 0.014
Integrated breast cancer pathway Wikipathways 3 (4.5%) <0.001 0.016
Polo-like kinase mediated events Reactome 2 (12.5%) <0.001 0.016
Herpes simplex infection - Homo sapiens (human) KEGG 4 (2.2%) 0.001 0.018
Cellular senescence Reactome 4 (2.1%) 0.001 0.018
C-MYB transcription factor network PID 3 (3.5%) 0.001 0.018
miRNA regulation of DNA damage response Wikipathways 3 (3.4%) 0.001 0.018
Cellular responses to stress Reactome 5 (1.5%) 0.002 0.018
B-WICH complex positively regulates rRNA expression Reactome 3 (3.2%) 0.002 0.018
Formation of the beta-catenin: TCF transactivating complex Reactome 3 (3.2%) 0.002 0.018

FDR: false discovery rate, PID: Pathway Interaction Database, KEGG: Kyoto Encyclopedia of Genes and Genomes.