Table 2.
Estimates from random effects models for longitudinal secondary outcome measures at 15 months
| Intravenous antibiotic therapy | Oral antibiotic therapy | Estimated mean difference (95% CI) | p value | |
|---|---|---|---|---|
| Percentage predicted FEV1 | 86·19 (1·10) | 84·11 (1·10) | 2·08 (−0·99 to 5·14) | 0·18 |
| Percentage predicted FVC | 94·08 (1·08) | 90·94 (1·08) | 3·14 (0·15 to 6·14) | 0·04 |
| Percentage predicted FEF25–75 | 72·39 (2·73) | 68·93 (2·45) | 3·46 (−3·74 to 10·66) | 0·35 |
| Oxygen saturation | 97·83 (0·09) | 97·78 (0·09) | 0·05 (−0·20 to 0·29) | 0·7 |
| Weight for age Z score | 0·11 (0·05) | 0·13 (0·05) | −0·02 (−0·15 to 0·11) | 0·79 |
| Height for age Z score | −0·34 (0·04) | −0·31 (0·04) | −0·03 (−0·13 to 0·07) | 0·57 |
| BMI Z score (paediatric) | 0·34 (0·05) | 0·33 (0·05) | 0·01 (−0·14 to 0·16) | 0·91 |
| BMI (kg/m2; adult) | 23·51 (0·22) | 24·25 (0·24) | −0·73 (−1·39 to −0·08) | 0·029 |
Data are mean (SE) estimated from model, unless otherwise indicated. Random effect model contains: baseline value, treatment group, time of follow-up measurement, and treatment group by time of follow-up measurement interaction term as independent variables in the model. BMI=body mass index.