Table 1.
Models of the association of DUP and 6-month PANSS score in the original (NEDEN) and replication (Outlook) datasets
|
NEDEN: all participants (n=734) |
NEDEN: non-affective psychosis (n=616) |
Outlook: all participants (n=194) |
||||
|---|---|---|---|---|---|---|
| Adjusted R2 | AIC | Adjusted R2 | AIC | Adjusted R2 | AIC | |
| Step change at 4 weeks | 0·013 | 6049 | 0·004 | 5089 | 0·008 | 1966 |
| Step change at 26 weeks | 0·029 | 6056 | 0·021 | 5089 | 0·002 | 1966 |
| 4 week step + linear effect | 0·021 | 6044 | 0·018 | 5085 | 0·009 | 1612 |
| Linear effect of DUP | 0·021 | 6057 | 0·018 | 5092 | 0·009 | 1611 |
| Square root of DUP* | 0·038 | 6044 | 0·033 | 5082 | 0·026 | 1608 |
| Log10DUP* | 0·043 | 6041 | 0·032 | 5083 | 0·040 | 1605 |
AIC=Akaike information criterion. DUP=duration of untreated psychosis. PANSS=Positive and Negative Syndrome Scale.
Curvilinear relationships of DUP and 6-month PANSS.