TABLE 1.

Correlated signaling pathways and upstream and downstream molecules related to cortactin-induced epithelial–mesenchymal transition (EMT).

Pathways	Upstream	Downstream	References
Rac1/PAK1/cortactin	P27, PAK1	ECM	Jeannot et al., 2017
Wg/Wnt signaling pathway	RNF128	CD44, c-Myc	Alicea et al., 2017; Wei et al., 2019
Rho GTPase Rac1 signaling Pathway	PODXL, CD44	FAK, Paxillin	Kim and Wong, 1995; El Sayegh et al., 2005
T3αvβ3 FAK/paxillin/cortactin/NWASP Arp2/3 signaling pathway	T3, FAK, Paxillin	NWASP, Arp2/3	Uzair et al., 2019
FAK/Src signaling pathway	Scr, P53	FAK, F-actin	Wang et al., 2013; Ungewiss et al., 2016
EGFR/Src/Arg/cortactin signaling pathway	Src, Arg, EGF	ECM	Mader et al., 2011; Ni et al., 2015