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. 2020 Oct 20;11:559674. doi: 10.3389/fendo.2020.559674

Table 1.

Cell type dependence of STARD1 mechanism.

Characteristic Y-1 Adrenal MA10 Testis In vivo Testis
Early Uncoupled Splicing Yes Yes Yes
Sustained slow splicing Yes NO Yes
Delayed mRNA increase YES YES YES
3.5kb mRNA dominant YES YES YES
Basal pRNA, spRNA, mRNA YES NO NO
Asymmetric Locus Activation YES YES YES
Paired mRNA-Mitochondria YES YES ?
Deletion activated LD YES YES YES
CRTC2 SIK S577A inhibit YES YES ?
Stimulation by SIK Inhibitor YES YES ?
High SIK1 induction YES YES ?
Acute Translation-Coupled CHOL Metabolism YES ? ?
Delayed ER-MAM Complex ? YES ?

See Figure 5 for graphic representation; Figures 711 for data.