Table 1.
Baseline demographics and clinical characteristics of the patients with early onset colon Adenocarcinoma.
| Characteristics | All patients, n (%) | Training set, n (%) | Validation set, n (%) |
|---|---|---|---|
| 2,348(100.0) | 1,644(70.0) | 704(30.0) | |
| Gender | |||
| Male | 1189(50.6) | 821(49.9) | 368(52.3) |
| Female | 1159(49.4) | 823(50.1) | 336(47.7) |
| Age | |||
| ≤37 | 402(17.1) | 296(12.6) | 106(15.1) |
| 38-47 | 1425(60.7) | 988(42.1) | 437(62.1) |
| ≥48 | 521(22.2) | 360(15.3) | 161(22.9) |
| Race | |||
| White | 1646(70.1) | 1126(68.5) | 520(73.9) |
| Black | 403(17.2) | 304(18.5) | 99(14.1) |
| Other* | 299(12.7) | 214(13.0) | 85(12.1) |
| Grade | |||
| Well | 145(6.2) | 104(6.3) | 41(5.8) |
| Moderately | 1760(75.0) | 1245(75.7) | 515(73.2) |
| Poorly | 367(15.6) | 249(15.2) | 118(16.8) |
| Undifferentiated | 76(3.2) | 46(2.8) | 30(4.3) |
| Tumor size | |||
| ≤2.4cm | 296(12.6) | 199(12.1) | 97(13.8) |
| 2.5-4.7cm | 892(38.0) | 642(39.1) | 250(35.5) |
| ≤4.7cm | 1160(49.4) | 803(48.8) | 357(50.7) |
| AJCC T stage (7th) | |||
| T1 | 218(9.28) | 147(8.9) | 71(10.1) |
| T2 | 265(11.3) | 187(11.4) | 78(11.1) |
| T3 | 1395(59.4) | 981(59.7) | 414(58.8) |
| T4a | 310(13.2) | 224(13.6) | 86(12.2) |
| T4b | 160(6.8) | 105(6.4) | 55(7.8) |
| AJCC N stage (7th) | |||
| N0 | 1085(46.2) | 751(45.7) | 334(47.4) |
| N1 | 739(31.5) | 527(32.1) | 212(30.1) |
| N2 | 524(22.3) | 366(22.3) | 158(22.4) |
| AJCC M stage (7th) | |||
| M0 | 1954(83.2) | 1374(83.6) | 580(82.4) |
| M1 | 394(16.8) | 270(16.4) | 124(17.6) |
| Regional nodes | |||
| Positive | 2324(98.9) | 1627(99.0) | 697(99.0) |
| Negative | 24(1.1) | 17(1.0) | 7(1.0) |
| Tumor deposits | |||
| Positive | 269(11.5) | 192(11.7) | 77(10.9) |
| Negative | 2079(88.5) | 1452(88.3) | 627(89.1) |
| Bone metastasis | |||
| Yes | 3(0.1) | 2(0.1) | 1(0.1) |
| No | 2345(99.9) | 1642(99.9) | 703(99.9) |
| Liver metastasis | |||
| Yes | 278(11.8) | 197(12.0) | 81(11.5) |
| No | 2070(88.2) | 1447(88.0) | 623(88.5) |
| Lung metastasis | |||
| Yes | 51(2.6) | 40(2.4) | 11(1.6) |
| No | 2297(97.8) | 1604(97.6) | 693(88.5) |
| Perineural invasion | |||
| Yes | 354(15.1) | 248(15.1) | 106(15.1) |
| No | 1994(84.9) | 1396(84.9) | 598(84.9) |
*American Indian/AK Native, Asian/Pacific Islander. AJCC, American Joint Committee on Cancer; TNM, tumor-node-metastasis.