Table 1. Baseline characteristics of participants in each group.
| Characteristics | Tolerance group | Intolerance group | P value |
|---|---|---|---|
| N | 97 | 35 | |
| Gender | 0.866 | ||
| Male | 68 (70.1%) | 24 (68.6%) | |
| Female | 29 (29.9%) | 11 (31.4%) | |
| Age | 61.1±18.3 | 59.1±17.8 | 0.593 |
| Hight | 168.0±7.4 | 170±8.9 | 0.208 |
| Weight | 64.9±11.4 | 67.8±11.2 | 0.202 |
| BMI | 23.4±4.2 | 23.6±2.3 | 0.788 |
| Comorbidities | |||
| Hypertension | 34 | 15 | 0.413 |
| CHD | 29 | 7 | 0.260 |
| Diabetes | 18 | 3 | 0.166 |
| CKD | 11 | 3 | 0.892 |
| Cirrhosis | 4 | 1 | 0.874 |
| COPD | 2 | 2 | 0.586 |
| Oncologic | 32 | 13 | 0.657 |
| Source of sepsis | |||
| Respiratory system | 21 | 9 | 0.623 |
| Abdominal | 28 | 13 | 0.364 |
| Urinary system | 4 | 1 | 0.857 |
| Skin and soft tissues | 27 | 8 | 0.567 |
| Bloodstream | 6 | 2 | 0.754 |
| Other | 11 | 2 | 0.531 |
| MV | 0.018* | ||
| No | 19 (19.6%) | 1 (2.9%) | |
| Yes | 78 (80.4%) | 34 (97.1%) | |
| Abdominal diseases | 0.935 | ||
| No | 63 (64.9%) | 23 (65.7%) | |
| Yes | 34 (35.1%) | 12 (34.3%) | |
| Feeding way | 0.681 | ||
| Jejunal tube | 19 (19.6%) | 8 (22.9%) | |
| Gastric tube | 78 (80.4%) | 27 (77.1%) | |
| EN total | 500.0 (300.0–700.0)# | 500.0 (200.0–500.0)# | 0.155 |
| EN speed | 41.8±36.3 | 36.7±21.1 | 0.435 |
| Lactate | 1.5±0.8 | 2.8±2.0 | <0.001* |
| Albumin | 31.4±3.9 | 32.2±7.0 | 0.400 |
| Hb | 106.5±27.3 | 89.5±13.4 | <0.001* |
| WBC | 11.2±6.7 | 10.5±4.8 | 0.553 |
| D-dimer | 5.7±4.7 | 5.0±3.8 | 0.464 |
| SOFA | 9.2±3.7 | 10.7±5.2 | 0.068 |
| APACHE II | 17.7±7.5 | 19.6±8.4 | 0.504 |
| AGI | 0.335 | ||
| 1 | 71 (73.2%) | 11 (31.4%) | |
| 2 | 18 (18.6%) | 13 (37.1%) | |
| 3 | 6 (6.2%) | 8 (22.9%) | |
| 4 | 2 (2.1%) | 3 (8.6%) |
*, P<0.05; #, median (Quartile1-Quartile). AGI, acute gastrointestinal abbreviated injury; APACHE, acute physical and chronic health assessment; BMI, body mass index; CHD, coronary heart disease; CKD, chronic kidney diseases; COPD, chronic obstructive pulmonary disease; EN, enteral nutrition; MV, mechanical ventilation; SOFA, sequential organ failure assessment.