Table S2. Statistical differences between EV bleeding and non-EV bleeding within 2 years.
| Variables | EV bleeding, n=710 (10.44%) | Non-EV bleeding, n=6,093 (89.56%) | P |
|---|---|---|---|
| Male, n (%) | 523 (73.66) | 4,307 (70.69) | 0.0984 |
| Age (years, mean ± SD) | 57.17±13.75 | 59.20±12.40 | <0.001 |
| Follow-up duration (months, mean ± SD) to bleeding | 6.30 (7.32) | 23.23 (3.76) | <0.001 |
| Etiology, n (%) | <0.001 | ||
| HBV | 259 (36.48) | 2,822 (46.32) | |
| HCV | 140 (19.72) | 1,193 (19.58) | |
| Alcohol | 105 (14.79) | 545 (8.94) | |
| Others | 206 (29.01) | 1,533 (25.16) | |
| Baseline laboratory value [mean (SD)] | |||
| AST (U/L) | 95.02 (131.6) | 89.86 (176.20) | 0.3371 |
| ALT (U/L) | 54.49 (62.08) | 64.60 (97.92) | 0.015 |
| Cr (mg/dL) | 1.39 (1.53) | 1.34 (1.57) | 0.1178 |
| Na (mEq/L) | 136.0 (11.64) | 137.3 (8.50) | <0.001 |
| K (mEq/L) | 4.06 (1.85) | 4.03 (1.10) | 0.1554 |
| Bilirubin-total (mg/dL) | 3.05 (4.77) | 2.58 (4.38) | <0.001 |
| Albumin (g/dL) | 3.04 (0.84) | 3.39 (0.83) | <0.001 |
| PT-INR | 1.35 (0.34) | 1.30 (0.52) | 0.0032 |
| Hb (g/dL) | 10.27 (2.52) | 11.59 (2.73) | <0.001 |
| WBC (×1,000/μL) | 7.14 (4.41) | 6.52 (3.95) | <0.001 |
| Platelet (×1,000/μL) | 111.30 (95.34) | 121.80 (75.64) | 0.5088 |
| r-GT | 208.40 (266.4) | 147.70 (238.1) | 0.0079 |
| Cholesterol | 154.60 (44.91) | 162.90 (47.48) | <0.001 |
| Antivirals for HBV % (n/N) | 35.9% (93/259) | 40.9% (1,175/2,822) | |
| Prognostic systems [mean (SD)] | |||
| CTP score | 6.84 (1.56) | 6.45 (1.53) | <0.001 |
| MELD score | 14.08 (5.90) | 13.09 (6.17) | <0.001 |
| MELD-Na score | 16 (8.04) | 14.83 (8.37) | <0.001 |
| PALBI score | −2.52 (0.69) | −2.66 (0.69) | <0.001 |
| Gamma-glutamyl transpeptidase-to-platelet ratio (GPR) | 4.04 (7.28) | 2.46 (4.51) | <0.001 |
| Gamma-glutamyl transpeptidase-to-albumin ratio (GAR) | 7.81 (13.82) | 5.56 (41.39) | 0.4374 |
| AST/ALT | 2.14 (1.82) | 1.66 (1.34) | <0.001 |
| AST to platelet ratio index (APRI) | 4.17 (8.20) | 3.60 (18.64) | 0.4724 |
| Platelet count to spleen diameter (PC/SD) | 18.87 (13.59) | 23.38 (17.26) | 0.0032 |
| Fibrosis-4-index (FIB-4) | 11.44 (24.11) | 9.12 (72.96) | 0.4764 |
| Fibrosis index (FI) | 3.85 (1.32) | 3.41 (1.18) | <0.001 |
| King’s score | 115.20 (288.6) | 120.1 (102.6) | 0.9605 |
| Lok score | 3.28 (3.53) | 2.41 (3.60) | <0.001 |
| Lok index | 0.85 (0.19) | 0.78 (0.22) | <0.001 |
| Portal vein size | 1.15 (0.25) | 1.11 (0.24) | 0.0034 |
| Forns index | 11.27 (2.07) | 10.72 (1.97) | 0.0056 |
EV, esophageal variceal; AST, aspartate aminotransferase; ALT, alanine aminotransferase.