Table S2. Factors associated with cardiovascular disease in patients with thyroid cancer.
| Variables | Primary CVD outcome | |
|---|---|---|
| Adjusted HR* (95% CI) | P value | |
| Age, 10 years | 1.59 (1.41–1.81) | <0.001 |
| Sex | ||
| Male | 1 (reference) | – |
| Female | 0.84 (0.620–1.13) | 0.252 |
| Type of surgery | ||
| Hemithyroidectomy | 1 (reference) | – |
| Total + subtotal thyroidectomy | 0.84 (0.62–1.13) | 0.239 |
| Levothyroxine median dose, 100 µg/day | 1.07 (0.86–1.33) | 0.548 |
| BMI (kg/m2) | ||
| <18.5 | 1 (reference) | – |
| <23 | 0.85 (0.37–1.95) | 0.694 |
| ≥23 | 1.28 (0.57–2.91) | 0.550 |
| SES | ||
| Upper (30%) | 1 (reference) | – |
| Mid (40%) | 1.01 (0.80–1.23) | 0.944 |
| Lower (30%) | 1.08 (0.83–1.41) | 0.576 |
| Smoking | ||
| Never | 1 (reference) | – |
| Ex-smoker | 0.77 (0.481–1.234) | 0.278 |
| Current | 1.311 (0.840–2.044) | 0.233 |
| Alcohol consumption | ||
| Never | 1 (reference) | – |
| <2 times a week | 1.07 (0.82–1.40) | 0.623 |
| ≥3 times a week | 0.81 (0.49–1.34) | 0.416 |
| Hypertension | 1.90 (1.49–2.41) | <0.001 |
| Diabetes mellitus | 1.14 (0.88–1.49) | 0.315 |
| Dyslipidemia | 0.98 (0.71–1.36) | 0.902 |
| CVD | 6.12 (4.87–7.69) | <0.0001 |
*, analyzed by multivariable Cox proportional hazards regression analysis.