Table 7. Detection of BRAFV600E mutation in three types of samples from PTC patients.
| Sample | cfDNA | FFPE | gDNA | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Coverage | VarReads | VarFreq | Coverage | VarReads | VarFreq | Coverage | VarReads | VarFreq | |||
| 2 | 6,187 | 0 | 0 | 1,117 | 252 | 22.56% | 490 | 0 | 0 | ||
| 3 | 4,759 | 0 | 0 | 546 | 118 | 21.61% | 828 | 0 | 0 | ||
| 5 | 1,651 | 0 | 0 | 618 | 70 | 11.33% | 906 | 0 | 0 | ||
| 6 | 2,299 | 0 | 0 | 538 | 151 | 28.07% | 771 | 0 | 0 | ||
| 7 | 1,497 | 0 | 0 | 806 | 205 | 25.43% | 787 | 0 | 0 | ||
| 8 | 4,841 | 0 | 0 | 122 | 22 | 18.03% | 664 | 0 | 0 | ||
| 9 | 3,900 | 0 | 0 | 407 | 49 | 12.04% | 497 | 0 | 0 | ||
| 10 | 1,572 | 0 | 0 | 571 | 26 | 4.55% | 857 | 0 | 0 | ||
BRAFV600E mutations were not detected in 3 types of samples in patient 1 and 4. PTC, papillary thyroid carcinoma; cfDNA, cell-free DNA; FFPE, formalin-fixed and paraffin-embedded.