Table 1.
The isotypes of the 14-3-3 proteins
| Gene | Chromo-some | Isotypes | ||
|---|---|---|---|---|
| YWHAB | 20q13.1 | Beta/Alpha | β/α | α is a phosphorylated form of β |
| YWHAE | 17p13.3 | Epsilon | ε | |
| YWHAG | 7q11.23 | Gamma | γ | |
| YWHAH | 22q12.3 | Eta | η | |
| YWHAQ | 2p25.1 | Tau/Theta | τ/θ | θ is an alternative name for τ |
| YWHAZ | 8q23.1 | Zeta/Delta | ξ/δ | δ is a phosphorylated form of ξ |
| SFN | 1p35.3 | Sigma | σ | |
Highly conserved seven isoforms of the 14-3-3 proteins have been identified. The α and δ are phosphorylated forms of the β and ξ, respectively and theta is an alternative name for tau. Genes encoding these isotypes are located at different positions of the human chromo-somes.